| Iowa State Cyclones Football vs. South Dakota Coyotes | 8-30-2025
Saturday
TBD | MidAmerican Energy Field at Jack Trice Stadium in Ames, IA | View Tickets |
| Iowa State Cyclones Football vs. Iowa Hawkeyes | 9-6-2025
Saturday
TBD | MidAmerican Energy Field at Jack Trice Stadium in Ames, IA | View Tickets |
| Arkansas State Red Wolves Football vs. Iowa State Cyclones | 9-13-2025
Saturday
TBD | Centennial Bank Stadium in Jonesboro, AR | View Tickets |
| Iowa State Cyclones Football vs. Arizona Wildcats | 9-27-2025
Saturday
TBD | MidAmerican Energy Field at Jack Trice Stadium in Ames, IA | View Tickets |
| Cincinnati Bearcats Football vs. Iowa State Cyclones | 10-4-2025
Saturday
TBD | Nippert Stadium in Cincinnati, OH | View Tickets |
| Colorado Buffaloes Football vs. Iowa State Cyclones | 10-11-2025
Saturday
TBD | Folsom Field in Boulder, CO | View Tickets |
| Iowa State Cyclones Football vs. BYU Cougars | 10-25-2025
Saturday
TBD | MidAmerican Energy Field at Jack Trice Stadium in Ames, IA | View Tickets |
| Iowa State Cyclones Football vs. Arizona State Sun Devils | 11-1-2025
Saturday
TBD | MidAmerican Energy Field at Jack Trice Stadium in Ames, IA | View Tickets |
| TCU Horned Frogs Football vs. Iowa State Cyclones | 11-8-2025
Saturday
TBD | Amon Carter Stadium in Fort Worth, TX | View Tickets |
| Iowa State Cyclones Football vs. Kansas Jayhawks | 11-22-2025
Saturday
TBD | MidAmerican Energy Field at Jack Trice Stadium in Ames, IA | View Tickets |
| Oklahoma State Cowboys Football vs. Iowa State Cyclones | 11-29-2025
Saturday
TBD | Boone Pickens Stadium in Stillwater, OK | View Tickets |
