| New Mexico United vs. El Paso Locomotive FC | 3-22-2025
Saturday
TBD | Rio Grande Credit Union Field at Isotopes Park in Albuquerque, NM | View Tickets |
| Birmingham Legion FC vs. El Paso Locomotive FC | 4-13-2025
Sunday
TBD | Protective Stadium in Birmingham, AL | View Tickets |
| Colorado Springs Switchbacks FC vs. El Paso Locomotive FC | 4-19-2025
Saturday
TBD | Weidner Field in Colorado Springs, CO | View Tickets |
| El Paso Locomotive FC vs. New Mexico United | 5-3-2025
Saturday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| Las Vegas Lights FC vs. El Paso Locomotive FC | 5-24-2025
Saturday
TBD | Cashman Field in Las Vegas, NV | View Tickets |
| El Paso Locomotive FC vs. San Antonio FC | 7-4-2025
Friday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| Sacramento Republic FC vs. El Paso Locomotive FC | 7-12-2025
Saturday
TBD | Heart Health Park in Sacramento, CA | View Tickets |
| Miami FC vs. El Paso Locomotive FC | 8-9-2025
Saturday
TBD | Pitbull Stadium in Miami, FL | View Tickets |
| El Paso Locomotive FC vs. Monterey Bay FC | 8-16-2025
Saturday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| El Paso Locomotive FC vs. Sacramento Republic FC | 8-23-2025
Saturday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| Phoenix Rising FC vs. El Paso Locomotive FC | 8-30-2025
Saturday
TBD | Phoenix Rising FC Stadium in Phoenix, AZ | View Tickets |
| El Paso Locomotive FC vs. Loudoun United FC | 9-3-2025
Wednesday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| North Carolina FC vs. El Paso Locomotive FC | 9-12-2025
Friday
TBD | WakeMed Soccer Park in Cary, NC | View Tickets |
| El Paso Locomotive FC vs. Charleston Battery | 9-20-2025
Saturday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| El Paso Locomotive FC vs. Oakland Roots SC | 10-1-2025
Wednesday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| Lexington Sporting Club vs. El Paso Locomotive FC | 10-11-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| El Paso Locomotive FC vs. FC Tulsa | 10-18-2025
Saturday
TBD | Southwest University Park in El Paso, TX | View Tickets |
| San Antonio FC vs. El Paso Locomotive FC | 10-25-2025
Saturday
TBD | Toyota Field - TX in San Antonio, TX | View Tickets |
